The paper presents analytical review of works on application of system approach in economic research. On this basis, the review concludes that further development of the system analysis of economic activities of the economic system on the basis of the relational paradigm requires the consideration of the substantial properties of the system elements that provide a particular result when they interact within a specific structure. Studies in the concept of a relational methodology, the features of the motion (of doing business) economic system within the area of its existence depending on the Manager’s decisions as the result of relations between individuals and the measured value information, reducing the uncertainty of doing business. It is established that the character of the movement is not linear with the presence of extreme points. It is shown that the extreme points characterize metastable or quasisteady with positive and different from zero profitability condition of the economic system, the coordinates of these points to specific economic systems are determined by their region of existence and the amount of gross output produced per unit of direct production costs.