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The purpose of the work was to identify economic, social, institutional, political factors of labor productivity in the regions of modern Russia. During the research based on cross-sectional statistics of 82 regions presented by Rosstat, linear econometric models of the set of independent influence, non-multicolarial factors on labor productivity in 2015–2017 were built. The level of explanation of the models was 94–95 %. Throughout the entire period, labor productivity, investment, foreign investment, wages, and a high number of government officials had a negative effect on productivity. During the period under review, factors that have a significant impact on labor productivity have changed. In 2017, foreign investment ceased to have a significant impact on productivity, began to have a significant positive impact on the use of advanced production technologies, the price index of consumer goods and the level of income inequality. The study showed that the composition of the factors determining labor productivity should reveal new factors that would enrich the economic science and allow more reasonably form economic policies aimed at increasing the productivity of labor.
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